LOW TESTOSTERONE

Treatment information guide

Testosterone deficiency is a medical condition that can lead to regular fatigue, rapid weight gain, diminished sex drive, erectile dysfunction, and low mood. With specialist care at Numan, it can be addressed and optimised.

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Explore our treatment options

We provide personalised care to ensure each patient receives the most effective treatment for their needs. Discover our range of treatment options, including testosterone replacement therapy, testosterone optimisation, and the Numan weight loss programme.

Testosterone replacement therapy

Testosterone replacement therapy (TRT) works by supplementing or replacing the body's natural testosterone levels when they’re insufficient. TRT can be administered in various ways including: pills, gels, and injections. Once administered, the exogenous testosterone enters the bloodstream and mimics the natural hormone's actions, restoring testosterone levels to a normal range and addressing the symptoms associated with testosterone deficiency.

KYZATREX®
Oral pill form TRT
Testogel®
Topical gel
Testosterone cypionate
Subcutaneous injection
Nebido® (testosterone undecanoate)
Intramuscular injection

Testosterone optimisation

Testosterone optimisation treatments work by stimulating the body's natural hormone production pathways to increase testosterone production, rather than directly supplying testosterone. They’re particularly useful for men who want to maintain fertility and testicular function while addressing symptoms of low testosterone, though they may be less effective in restoring testosterone levels to the same degree as direct testosterone replacement therapies.

Clomiphene
Oral pill
Zivafert (HCG)
Subcutaneous injection

Testosterone supplements

Testosterone supplements can help support the body's natural testosterone production by providing essential vitamins, nutrients, and compounds that support hormone health.

High Strength Testosterone Supplement
Fast-dissolving powder drink

Weight loss programme

Excess body fat, particularly visceral fat, can contribute to lower testosterone levels. Fat tissue contains aromatase, an enzyme that converts testosterone into oestrogen.¹ By reducing fat mass, the conversion of testosterone to oestrogen decreases, potentially leading to higher testosterone levels.² Obesity is often linked to insulin resistance, which can negatively impact testosterone levels.³ The use of GLP-1 medications in men may therefore help restore normal testosterone levels through weight loss mechanisms.³

GLP-1 medications (Wegovy & Mounjaro)
Subcutaneous injection

Symptom management

Erectile dysfunction (ED) is a prevalent symptom among men with low testosterone and can be treated with medication. However, ED medications do not address the underlying hormonal imbalance. Treating the testosterone deficiency with TRT is the optimal approach if low testosterone is contributing to ED.

Tadalafil Daily
Oral pill

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References

¹ Cohen PG. Aromatase, adiposity, aging and disease. The hypogonadal-metabolic-atherogenic-disease and aging connection. Med Hypotheses [Internet]. 2001;56(6):702–8. Available from: http://dx.doi.org/10.1054/mehy.2000.1169

² Okobi OE, Khoury P, De la Vega RJ, Figueroa RS, Desai D, Mangiliman BDA, et al. Impact of weight loss on testosterone levels: A review of BMI and testosterone. Cureus [Internet]. 2024; Available from: http://dx.doi.org/10.7759/cureus.76139

³ Grossmann M, Tang Fui M, Dupuis P. Lowered testosterone in male obesity: Mechanisms, morbidity and management. Asian J Androl [Internet]. 2014;16(2):223. Available from: http://dx.doi.org/10.4103/1008-682x.122365

Low Testosterone Treatment Options