Since your recent blood test showed low testosterone levels, it’s important to address this deficiency. To confirm your diagnosis and begin treatment, please schedule a follow-up venous blood test at least four weeks after your initial test. This test includes an online doctor consultation, which you’ll be able to book once your test results are back.
Price from:£200.00£149.00 / blood test + doctor consultation
If your venous blood test indicates normal testosterone levels, we will reimburse the full cost of the test and doctor consultation since treatment will not be necessary.
TRT doctor consultation included to discuss your results and treatment plans
43 biomarkers tested to ensure we provide the most suitable treatment for you
Results in 3-5 days for a quick start to treatment
Direct access to Patient Support Managers to ensure ongoing support
If you're unsure about how to proceed with your testosterone deficiency treatment, we're here to help. Feel free to schedule a free consultation with our Patient Support Managers.
In her role as Patient Support Manager for low testosterone, Samantha is dedicated to helping you with any questions or concerns you may have before and during your treatment. Samantha is a dedicated advocate for health and well-being, dedicated to empowering individuals to recognise and implement meaningful health improvements in their lives.
As a Patient Support Manager for low testosterone, Greg is dedicated to helping you with any questions or concerns you may have before and during your treatment. Greg’s approach focusses on problem-solving, fostering strong relationships, and enhancing healthcare accessibility. Greg finds pride in being part of a team that empowers patients to achieve their optimal health.
We get a complete picture of your health to make sure we provide the most suitable treatment for you.
Hormone levels
Anaemia
Heart health
Kidney & liver function
Diabetes
Prostate health
We assess all vital biomarkers to identify the right and safe treatment based on your health profile. Click on each biomarker to get insights into what it is and how it affects your health.
Origin: Also known as primary testicular failure, primary hypogonadism arises directly from problems within the testicles.
Common causes: The causes of primary hypogonadism can be diverse, ranging from genetic disorders like Klinefelter's Syndrome to physical issues such as undescended testicles, testicular injury, or the effects of cancer treatment. Ageing can also play a significant role in its development.
In these cases, the testicles themselves are impaired and fail to produce sufficient levels of testosterone.
Origin: Secondary hypogonadism arises from issues in the brain regions that control the testicles—the hypothalamus or the pituitary gland.
Common causes: Causes of secondary hypogonadism can include genetic conditions like Kallmann syndrome, inflammatory diseases, HIV/AIDS, certain medications, or even obesity.
In these cases, the testicles might be healthy but are not receiving enough hormonal signals to function properly.
Even before birth, your testes start producing small amounts of testosterone. Levels increase throughout childhood and peak significantly during adolescence. By your early 20s, testosterone levels reach their highest point.
For adult men, a normal testosterone level ranges from 12 to 29 nmol/L.
These values do not account for age-related decline or individual symptoms, which your doctor will consider when interpreting your levels.
If your testosterone levels are less than 12 nmol/L and you have symptoms, you may benefit from testosterone replacement therapy (TRT) or alternative testosterone-boosting medications.
A 2022 study examined testosterone levels in 1,486 men aged 20 to 44. They determined normal testosterone levels for each age bracket by using the middle third of the data.
If these symptoms are holding you back, you might benefit from Testosterone Replacement Therapy (TRT).
Erectile dysfunction
Decreased libido
Fatigue
Poor sleep
Mood changes
Difficulty concentrating
Loss of muscle mass
Increased body fat
Reduced facial and body hair growth
Testosterone replacement therapy (TRT) works by supplementing or replacing the body's natural testosterone levels when they’re insufficient. TRT can be administered in various ways including: pills, gels, and injections. Once administered, the exogenous testosterone enters the bloodstream and mimics the natural hormone's actions, restoring testosterone levels to a normal range and addressing the symptoms associated with testosterone deficiency.
Kyzatrex is an immediate-release oral pill containing the active ingredient testosterone undecanoate. It’s absorbed through the lymphatic system, bypassing the liver, and is then broken down by enzymes into testosterone, which the body can use.
An oral pill taken twice daily with food
In a six-month study involving 127 men diagnosed with testosterone deficiency, several significant health improvements were observed:
96% of the participants achieved normal testosterone levels within three months.
There was a twofold increase in mean free testosterone levels.
Notable improvements were recorded on the Aging Males’ Symptoms (AMS) scale
Benefits:
Convenient to take
Flexible dosing
Achieves stable testosterone levels (limits peaks & troughs)
Limitations:
Can increase blood pressure
Prior to treatment: Two blood tests and one blood pressure reading
1 month after treatment: One blood test and one blood pressure reading
3 months after treatment: One blood test and one blood pressure reading
6 months after treatment, and every 6 months thereafter: One blood test and one blood pressure reading
Testogel is a topical gel that delivers testosterone through the skin via transdermal absorption, allowing it to enter the bloodstream and increase overall levels. Applied daily, Testogel helps maintain stable testosterone levels throughout the day.
Applied once a day in the morning, to the upper arms and shoulders
Comes in a pump form, delivered monthly
In a placebo-controlled trial with 274 patients, 82% (139 out of 169) of the men with hypogonadism who were treated with an optimised dose of testosterone gel attained normal testosterone levels within six months.
Benefits:
Convenient to apply
Flexible dosing
Achieves stable testosterone levels
Limitations:
Risk of transfer through skin-to-skin contact, requiring extra care during and after application
Can cause localised skin reactions
Factors such as sweating and showering can affect absorption, and consequently the effectiveness of the dose taken
Prior to treatment: Two blood tests and one blood pressure reading
1 month after treatment: One blood test and one blood pressure reading
3 months after treatment: One blood test and one blood pressure reading
6 months after treatment, and every 6 months thereafter: One blood test and one blood pressure reading
Testosterone cypionate is a short-acting injection that works by steadily releasing testosterone into the bloodstream, replacing the testosterone your body is unable to make.
A small injection self-administered on alternate days into subcutaneous fat (usually found around the abdomen)
Injectable TRT is effective at restoring testosterone levels to normal, with most effects starting to take place within 6 months after initiating treatment. The alternate-day dosing of testosterone cypionate allows for better testosterone level stability.
Benefits:
Flexible dosing
Achieves stable testosterone levels
Limitations:
You have to self-inject every other day
Absorption varies from person to person
Requires extra care when handling and storing equipment
Prior to treatment: Two blood tests and one blood pressure reading
1 month after treatment: One blood test and one blood pressure reading
3 months after treatment: One blood test and one blood pressure reading
6 months after treatment, and every 6 months thereafter: One blood test and one blood pressure reading
Nebido is a long-acting TRT containing testosterone undecanoate as the active ingredient. It’s suspended in an oily solution and injected into a muscle, where it’s gradually released over time. This slow-release formula ensures that your testosterone levels remain stable without causing a buildup in your blood.
Nebido is administered by a clinician every 10 to 14 weeks into the buttocks.
In a study of 133 patients with erectile dysfunction and low testosterone levels, 1,000 mg of TU was administered initially, then again at 6 and 18 weeks. Over a period of 6 months, the study observed several significant health improvements in patients:
Total testosterone levels increased by 183%
Free testosterone levels increased by 181%
Cholesterol levels decreased
Erectile function improved in 77% of the patients
Significant improvements were noted on the Ageing Males’ Symptoms (AMS) scale
Safety tests showed increases in haemoglobin, hematocrit, and PSA, but all remained within normal ranges, with no serious side effects observed.
Benefits:
Injections only once every 3 months
Injected by a clinician
Limitations:
Requires post-injection monitoring
Intramuscular injections can be painful
It can be harder to achieve stable testosterone levels with injections since you're committed to the dose for three months.
Prior to treatment: Two blood tests and one blood pressure reading
3 months after treatment: One blood test and one blood pressure reading
6 months after treatment: One blood test and one blood pressure reading
9 months after treatment: One blood test and one blood pressure reading
12 months after treatment, and every 6 months thereafter: One blood test and one blood pressure reading
Testosterone optimisation treatments work by stimulating the body's natural hormone production pathways to increase testosterone production, rather than directly supplying testosterone. They’re particularly useful for men who want to maintain fertility and testicular function while addressing symptoms of low testosterone, though they may be less effective in restoring testosterone levels to the same degree as direct testosterone replacement therapies.
Clomid, traditionally a fertility treatment for women, is used off-label to treat men with low testosterone and low sperm counts by correcting hormonal imbalances and boosting hormone production. As a selective oestrogen receptor modulator, Clomid blocks oestrogen's effects, increasing the production of follicle-stimulating hormone (FSH) and luteinising hormone (LH), which promote the production of sperm and testosterone.
It’s important to note that Clomid is not a testosterone replacement product, but a testosterone optimisation medication.
Clomid is taken orally, every day.
Seventeen studies looked at the effectiveness of clomiphene citrate on hypogonadal men, with 1279 patients. The review showed that clomiphene citrate treatment significantly increased total testosterone levels and other related hormones, improving symptoms, with side effects reported in less than 10% of patients.
However, studies show that it takes longer for testosterone levels to rise and symptoms to improve for men taking clomiphene than it does for those using TRT.
Benefits:
Preserves fertility
Stimulates natural testosterone production
Convenient and flexible dosing
Limitations:
Variable response
Off-label use, therefore less researched
Prior to treatment: Two blood tests and one blood pressure reading
1 month after treatment: One blood test and one blood pressure reading
3 months after treatment: One blood test and one blood pressure reading
6 months after treatment, and every 6 months thereafter: One blood test and one blood pressure reading
Zivafert is a treatment that mimics the effect of luteinising hormone and stimulates your testicles to naturally produce more testosterone, unlike TRT which adds testosterone to your body. This helps maintain testosterone levels and maintain fertility by maintaining sperm production. It can be used as a treatment on its own but it can also be used alongside TRT to support fertility maintenance.
A small injection self-administered every Monday, Wednesday, and Friday into subcutaneous fat (fat around the abdomen).
A review of 42 men with low testosterone at Men’s Health Boston found that HCG monotherapy, starting with a dose of 1500IU three times a week, significantly improved testosterone levels in 95% of the men over an average follow-up of 13 months.
Another study of 20 men treated with HCG for hypogonadism showed similar results, with significant increases in testosterone levels and 50% of patients reporting symptom improvement with no side effects over 6 months.
Benefits:
Preserves fertility
Stimulates natural testosterone production
Limitations:
Variable response
Off-label use, therefore less researched
Have to inject three times per week
Prior to treatment: Two blood tests and one blood pressure reading
1 month after treatment: One blood test and one blood pressure reading
3 months after treatment: One blood test and one blood pressure reading
6 months after treatment, and every 6 months thereafter: One blood test and one blood pressure reading
