ERECTIONS ∙ 3 minute read

Can you take PE & ED medication together?

By Joe Young | Medically reviewed by Dr Luke Pratsides

Imagine the dilemma: ejaculate too soon, or risk losing your erection. A nasty pairing of frustration. Premature ejaculation (PE) and erectile dysfunction (ED) can go hand in hand. And when it comes to sex, you don’t want to miss your shot. 

Let’s see which treatments can be combined to tackle the issue on both fronts. 

How are PE & ED related?

They’re the two most common male sexual problems and the root causes are often the same. High-stress levels, performance anxiety, and relationship problems are just a few examples that can cause both problems in the bedroom. 

ED can even lead to the development of PE. Picture the scene. You’re getting intimate, all the while focusing on staying hard. Arousal is high, but that leads to the point of no return faster than you’d like. Or, to avoid going soft, you try to cool off. Which leads to loss of erection. 

It’s a tightrope walk where enjoyment takes a back seat. It can lead to disappointment, frustration, or embarrassment. Not exactly feelings associated with enjoyable sex. 

Which medications can be used together?

There are many medications to treat both ED and PE. Sometimes they can even be used together - a double team to fight on both flanks.

Let’s take a look. 

Delay Wipes and Delay Spray contain numbing agents such as lidocaine, which numbs your penis before sex, making you last longer. There is no interaction between topical anaesthetics and ED treatments like Sildenafil or Tadalafil, so they’re safe to use together. 

Paroxetine can be combined with either  ED treatment. In fact, studies have shown that a combination of paroxetine and sildenafil can achieve better results for PE than paroxetine alone. Double down for twice the reward. 

However, it’s not safe to take Priligy with sildenafil or tadalafil. Together, these drugs can cause low blood pressure, which could bring it to dangerous levels if combined, resulting in severe dizziness, feeling faint, or even collapse.

Alcohol is often thought of as a solution to PE - but it can have the opposite effect. Drinking large amounts can make it hard to get or keep an erection, or make it hard to have an orgasm at all. It also causes low blood pressure so should be avoided when taking Priligy, sildenafil, or tadalafil. 

Our clinicians can talk you through the options when you make a purchase. 

Other ways to help PE & ED

1. Learn to relax

On both fronts, relaxing is key. If you relax, you’re more likely to stay hard and you’re also less likely to come fast. Incorporating relaxation techniques, or discussing it with your partner are steps towards better sex. 

2. Keep practising

Take the pressure out of it. Try methods like the stop-and-start technique for PE or practise losing and gaining an erection for ED. It’s better to realise they come and go. 

3. Do pelvic floor exercises

Yes, men can do this too. Squeezing the muscles you use to hold in urine or gas a few times a day, in quick and long bursts, can help you control erections and ejaculations. 

Paroxetine

Paroxetine

Harness control over ejaculation.

The numan take 

Do something about erectile dysfunction and premature ejaculation. It’s a confidence killer, but Delay Wipes, Delay Spray, and Paroxetine can be combined with sildenafil or tadalafil to attack the problem on all fronts, giving you the power to enjoy sex again.