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Evidence over assumption
From clinical trials to everyday life: We don't assume, we measure. We test what others take for granted.
Science & research
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We study the science of improving health, at a scale few others can match, and we publish what we find.
The science of a longer healthspanÂ
Healthspan is the years you live in good health, and it’s what our research aims to understand. We study how treatment, behaviour change, and technology work together to extend it, drawing on one of the UK’s largest patient populations and presenting our findings at the world’s leading scientific congresses.
Our research
Proof, in numbers
Our clinical research, in numbers.
15
Conference abstracts presented and papers published
8
Peer-reviewed abstracts presented at scientific congresses
33,168
Patients in our largest safety evaluation
800,000+
People who have come to Numan to improve their health
WHY WE RESEARCH
Longer, healthier lives need better evidence
Good medicine needs evidence of every kind: trials that establish what a treatment can do, and large-scale studies of what happens when people fit treatment around jobs, families, and everything else. Our clinical research team works across that spectrum, following tens of thousands of patients over months and publishing the results.
We research treatment outcomes, behaviour, patient safety, and the responsible use of AI in care. We started with obesity, and we’re now studying men’s and women’s hormonal health too.
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Better evidence, better products
What we learn feeds back into what we build.
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Trust through transparency
We publish our research openly, so you don't have to take our word for it.
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Adding to the field
What we publish is there for any clinician or researcher to use.
THE EVIDENCE
What our evidence shows
The more you engage, the more you lose
We followed 18,390 adults living with obesity who started tirzepatide through Numan. People who used the programme regularly lost an average of 21% of their body weight at nine months. Those who dipped in and out lost 16.6%. The gap showed up from month three and stayed.
Presented at Obesity Week 2025. Griffiths Z, Henderson B, Sacher PM, et al.
AI support with real clinicians behind it
Expert health coaches reviewed 26,654 conversations between patients and our AI health assistant over 12 months. 99% were rated safe, 99% accurate, and none contained clinical misinformation. In 4% of conversations the AI brought in a clinician, because the patient needed clinical input.
Presented at Obesity Week 2025. Griffiths Z, Henderson B, Sacher PM, et al.
Treatment quietens food noise
Food noise is the constant, intrusive thinking about food that makes losing weight harder. Among 288 patients on weight loss medication through our programme, 68% said it eased. Scores on the Food Noise Questionnaire fell from 15 to 11 on average, and the number with the most severe scores halved.
Presented at Obesity Week 2025. Griffiths Z, Henderson B, Sacher PM, et al.
PEOPLE
The experts behind the research
Our researchers and advisors work with leading institutions including the University of Cambridge, Ulster University, and Durham University. Our research has been presented at the European Congress on Obesity, Obesity Week, the UK Congress on Obesity, and others.
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Head of Clinical Research
Dr Rebecca Jones, BSc, MPh, PhD
Rebecca holds a PhD from the University of Cambridge and has spent 13 years in digital healthcare and clinical research. She has over 30 peer-reviewed publications on obesity, behaviour change, and long-term weight health.
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VP of Behavioural Medicine
Zoe Griffiths, BSc, RD
A registered dietitian for over 20 years and a SCOPE-certified obesity practitioner, Zoe led global science at WeightWatchers International and behavioural medicine at Allurion. She sits on the British Dietetic Association's Obesity Specialist Group committee.
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Chief Medical Strategy Officer
Dr James King, MBBS, PhD
James leads clinical strategy for Numan's healthspan mission, from preventative care to precision medicine. His research began at Cambridge, modelling sudden cardiac death, and now spans AI across healthcare, with over 500 citations and an honorary post in Computer Science at Durham. He co-founded Eos Analytics and, as CMO at Evergreen Health Solutions, built AI tools now supporting over three million NHS patients.
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GP and Men's Health Specialist
Dr Zak Zafrani, MBChB (Hons), MRCGP, DPD, FRSPH
Zak works across metabolic health and sports medicine, including testosterone replacement therapy (TRT) in athletes and platelet-rich plasma (PRP) in recovery. He received the 2025 Emerging Scholars Award from the Androgen Society.
Research library
Read our abstracts
All our abstracts, presented or accepted for presentation at scientific congresses, collected in one place.
Oral presentation
Integrated Personalised Medicine 2026
2 abstracts
European Congress on Obesity 2025
Reports
Numan reports
Research that reaches beyond the clinic. Our reports track how the UK understands obesity and what it costs the country to get it wrong.
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The State of Obesity 2025
Our annual survey of UK public attitudes to obesity. The blame narrative is weakening and medical understanding is rising, but less than half of Britons recognise obesity as a disease, and stigma remains the biggest barrier to care.
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The State of Obesity 2024
Our inaugural report, understanding where the national conversation regarding obesity as a disease stood one year after the MHRA's approval of tirzepatide for weight loss and chronic weight management in eligible adults.
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The economic case for treating obesity
Produced with Health Policy Partners and with contributions from Professor Alex Miras (University of Ulster) and experts from the Tony Blair Institute and UKAI, this white paper models what obesity costs the UK in lost productivity, and the potential economic impact.
Work with us
Media: For interviews with our research team or comment on obesity science, contact the press office below.
Research partnerships: From clinical trials to large-scale real-world evidence studies, we partner on research across our platform. Get in contact with our team at: [email protected]
Open Roles: See below.
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