MEDICATED WEIGHT LOSS

Mounjaro

Numan Weight Loss Programme starting from:£20.00 / month

Subject to clinical suitability. Price related to a 12-month plan. Ongoing monthly pricing varies based on your final plan.

How it works: GIP and GLP-1 receptor agonists suppress appetite, reduce cravings, and improve blood sugar levels

Effectiveness: Drives an average of 22.5% body weight reduction¹

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Hassan

All content on this page has been medically reviewed by: Hassan Thwaini, Clinical Pharmacist and Copywriter, Master of Pharmacy (MPharm) on 22 January, 2026. GPhC Registration: 2221320View profile

What is Mounjaro?

Mounjaro (tirzepatide) is a new medication licensed for weight loss in certain groups of people. The active ingredient (tirzepatide) was originally designed for use in the treatment of type 2 diabetes,¹ used to help manage blood sugar levels more effectively, but due to positive impact on peoples weight being seen it was approved for use in the treatment of obesity in 2023.

Taken once a week through a simple injection, Mounjaro is now licensed for use as a weight loss medication.¹

How effective is Mounjaro?

Mounjaro has shown great results for weight loss. Clinical studies have shown that people using Mounjaro lose more weight compared to those on other weight loss medications.

  • Patients lost an average of 9.81 kg (about 21.6 lbs) compared to placebo, with even higher reductions at higher doses.²

  • Weight loss increased with higher doses (5 mg, 10 mg, and 15 mg) demonstrating a clear dose-response relationship.²

  • More participants achieved at least 5%, 10%, and 15% body weight reductions compared to those on placebo or other diabetes medications.²

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How does Mounjaro work?

Mounjaro has a unique approach to weight loss, as it targets two key pathways in the body. Here’s how it works:¹

  • Reduces appetite: Mounjaro helps to control hunger by affecting hormones that signal fullness, so you feel satisfied with less food.

  • Boosts insulin sensitivity: It improves how your body uses insulin, which helps keep blood sugar levels stable and prevents energy crashes.

  • Increases adiponectin levels: This hormone plays a role in regulating glucose levels and breaking down fatty acids, further supporting weight loss.

  • Long-lasting effects: With a half-life of five days, Mounjaro stays active in your system, allowing for convenient once-weekly injections.

  • Proven results: Clinical studies have shown weight reductions of 16.5% to 22.5% over 72 weeks, even in patients without diabetes.

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Why choose Numan for Mounjaro?

Numan isn't just an online pharmacy. We’re a holistic health provider offering complete care to help you get the most from your treatment. When you choose Mounjaro with Numan, you’ll also get access to:

Mounjaro treatment dosages

When starting Mounjaro, the dosage is gradually increased through a process called dose titration. This step-by-step approach allows your body to adjust to the medication smoothly and helps to minimise any potential side effects.²

It’s worth noting that not everyone will need the highest dose to see effective results. Your maintenance dose will depend on how your body responds throughout the treatment.²

DoseUsePrice
2.5mgInjected into the upper (subcutaneous) layer of the skin once a week. Dose is then titrated based on individual response.£219
5.mgInjected into the upper (subcutaneous) layer of the skin once a week. Dose is then titrated based on individual response.£249
7.5mgInjected into the upper (subcutaneous) layer of the skin once a week. Dose is then titrated based on individual response.£299
10mgInjected into the upper (subcutaneous) layer of the skin once a week. Dose is then titrated based on individual response.£319
12.5mgInjected into the upper (subcutaneous) layer of the skin once a week. Dose is then titrated based on individual response.£339
15mgInjected into the upper (subcutaneous) layer of the skin once a week. Dose is then titrated based on individual response.£359

Mounjaro doses

2.5mg

Starting dose.

5-7.5mg

5mg is the first maintenance dose, often prescribed after 4 weeks. 7.5mg is then available via a dose increase request .

10-15mg

10mg and 15mg are the higher maintenance doses, achieved by titrating up by 2.5mg every 4 weeks.

Who is eligible for Mounjaro?

Mounjaro is recommended for managing obesity as part of a comprehensive plan that includes a reduced-calorie diet and increased physical activity. To be eligible for Mounjaro, you must meet the following criteria:3

  • An initial BMI of at least 30 kg/m².

  • Or a BMI of 27 kg/m2 to <30 kg/m2 (overweight) in the presence of at least one weight-related comorbid condition.

Mounjaro is designed to support significant weight loss alongside lifestyle changes, helping to improve health outcomes for those at higher risk due to obesity. If you fit these criteria, then you may be eligible for treatment.

Who should not take Mounjaro?

You shouldn't take Mounjaro if you:

  • Are pregnant or breastfeeding

  • Have a history of medullary thyroid cancer or MEN2 syndrome

  • Have severe gastrointestinal disease or pancreatitis

  • Are allergic to tirzepatide or any pen components

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How to use Mounjaro

Taking Mounjaro is simple and straightforward. It comes in a pre-filled injection pen that you take once a week. You can inject Mounjaro in the following areas:

  • Stomach: At least 2 inches away from your belly button.

  • Thighs: Either thigh is suitable, just avoid the inner thigh.

  • Upper arm: The back of the upper arm if someone else is administering the injection.

Make sure to rotate the injection site each week to prevent irritation. Avoid areas that are bruised, red, or sore. After use, simply dispose of the pen safely in a yellow sharps bin and you’re good to go.

Step 1: Prepare your pen

• Select the correct Mounjaro KwikPen with your prescribed weekly dose.

• Check the pen: make sure the medication is clear and colourless/slightly yellow, and that the pen is undamaged and within its expiry date.

• Pull off the pen cap.

• Wipe the red inner seal with an alcohol wipe.

• Always use a new needle. Inspect the needle packaging and cap for damage. If damaged, dispose and use a new one.

• Remove the paper tab from the needle. Push it straight onto the pen and twist until secure.

• Remove both the outer and inner caps from the needle.

• Prime the pen: turn the dose knob slowly until you hear two clicks and the extended line appears in the dose window (this is the prime position).

• Hold the pen with the needle pointing up. Gently tap the cartridge holder to move air bubbles to the top.

• Push in the dose knob fully and count to 5. ‘0’ should appear in the dose window and a drop of medicine should come out.

• If no medicine appears, repeat up to 2 more times. If still no drop, change the needle and try again.

Step 2: Choose your injection site

• You can inject into your stomach (at least 2 inches away from your belly button) or the front of your thighs.

• If someone else is helping, they can inject into your upper arm.

• Rotate injection sites each week to avoid irritation, even if using the same general area.

• Make sure the skin is clean and undamaged. Clean with an alcohol wipe and allow to dry.

Step 3: Inject the dose

• Turn the dose knob until it stops and the ‘1’ is shown in the dose window.

• Position the pen firmly against your skin where you plan to inject.

• Push the pen down with steady pressure, then press and hold the dose knob until it stops.

• Count to 5 slowly while holding the knob.

• Ensure the ‘0’ appears in the dose window before removing the needle from your skin.

• If you notice any blood, press gently with a tissue—do not rub the area.

Step 4: Dispose and store safely

• Without touching the needle, guide it into the outer needle cap placed on a flat surface.

• Once the needle is covered, push the outer cap on fully.

• Unscrew the needle and dispose of it in a sharps bin.

• Never recap the inner needle—this can lead to accidental injury.

• Always remove the needle after each injection to prevent blockages, infection, and incorrect dosing.

• Replace the pen cap and store the pen properly, away from light.

If you’re ever unsure, contact a Numan clinician for help.

If you miss a dose of Mounjaro, you should take it within 4 days. If more than 4 days have passed you should skip the dose and take your next one on your usual day.

There isn't a one-sized-fits-all timeframe for how long an individual needs to use Mounjaro. For some people, a shorter treatment duration may suffice. For others, they may find the benefits are needed lifelong.

Watch the how-to video

Things you should know about Mounjaro

When you place your first order, we’ll set you up with everything you need to get started:

  • A sharps bin for safe disposal

  • Needles, plus a spare just in case

  • Alcohol wipes to keep things clean

  • Your Numan Programme Guide packed with tips, info, and everything you need to start treatment

  • Your treatment

  • Guidance on downloading and using the Numan app

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Keep your Mounjaro KwikPen in the refrigerator at 2°C to 8°C. Do not freeze it. If needed, Mounjaro can be stored unrefrigerated for up to 30 days, as long as the temperature stays below 30°C. After 30 days out of the fridge, the pen must be discarded, even if it hasn’t been used. Always check the expiry date before use. The shelf life of a refrigerated, unopened pen is 24 months, and the expiry date of your pen will be printed on the box.

While Mounjaro is generally well-tolerated, some people may experience side effects, primarily gastrointestinal, such as nausea, diarrhoea, and vomiting (may affect up to 1 in 10 people), especially during the initial phase of treatment. These side effects are usually mild to moderate and tend to decrease over time. It's important to read the Patient Information Leaflet provided with your package and consult your healthcare provider for a comprehensive list of side effects and advice on managing them.

For more information, please visit this page.

Report any of the following to your clinician:

  • Persistent vomiting or diarrhoea

  • Unexplained abdominal pain

  • Visual changes

  • Severe allergic reactions

The duration of Mounjaro treatment depends on individual health goals and response to the medication. Implementing lifestyle changes alongside the treatment is crucial for sustained weight management. By building healthier habits you should be able to sustain your weight beyond taking the medication. Your healthcare provider will guide you on the appropriate duration based on your progress and overall health.

Tirzepatide may affect how your body absorbs some medicines. Always disclose medications during your consultation.

  1. Complete a short health assessment

  2. A Numan clinician reviews your case

  3. If approved, your treatment is shipped discreetly

  4. Access ongoing support and renew easily

The difference between Mounjaro and Wegovy

It can be difficult to choose the right weight loss medication. However, a consultation with a Numan clinician can help you make a more informed decision. Below is a short summary of what the main differences are between Mounjaro and Wegovy.1,4

MounjaroWegovy
Achievable weight loss, according to researchUp to 22.5%Up to 18%
Protects against heart diseaseNoYes
DosageOne weekly injectionOne weekly injection

Meet the experts

At Numan, our Weight Loss Programme is crafted by a team of dedicated experts in the fields of obesity management, behavioural change, and metabolic health.

With treatments like Mounjaro, which combines GLP-1 and GIP receptor agonists to suppress appetite and improve blood sugar regulation, our experts have designed a holistic programme that pairs advanced medications with personalised health guidance for maximum impact.

From nutritionists to behavioural psychologists, each expert brings a unique perspective to enhance your journey and help you lose weight effectively and sustainably.

OTHER SOLUTIONS

Effective treatments for weight loss

Proven solutions to change your weight, mindset, and behaviour.

Personalised health coaching

Health coaching is the backbone of lasting change in our programme. Alongside Mounjaro, our health coaches are here to support you in building sustainable habits in nutrition, exercise, sleep, and mindset.

While Mounjaro suppresses hunger and reduces food cravings, our coaches help you optimise these effects by guiding you toward a balanced lifestyle. From tips on satisfying, nutritious meals, to creative ways to integrate movement into your day, our coaches are committed to helping you unlock the full potential of your treatment.

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Obesity: fighting the disease with effective treatment

At Numan, we treat obesity not simply as a symptom but as a complex, chronic disease influenced by factors like genetics, hormones, and environment.5 Our approach recognises that effective treatment requires more than lifestyle changes alone - it demands a targeted medical response.

Mounjaro plays a critical role in this treatment plan by helping to reduce appetite and regulate blood sugar levels, making it easier to maintain a balanced diet and achieve weight loss goals. By addressing obesity as a disease, we’re able to support you with an evidence-backed, compassionate approach that integrates effective treatment, expert support, and personalised coaching.

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REAL PEOPLE, REAL IMPACT

Over 800,000 people have trusted us to improve their health

I've done the reprogramming bit. Now I get to live my life having had that help. I feel better in myself - I'm not scared to look in the mirror.
helen
I feel like I'm bouncing up the hill on the school run, whereas before I'd wonder why I was doing this. The whole household eats differently now.
sarah
I go out camping now. I do all sorts. I've got shirts I hadn't worn for 20 years and I get to wear them again.
craig

Your health partner

Healthcare at
your fingertips

Connect with our clinicians and your personal health coach. Monitor your progress, set reminders, and get personalised advice.
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FAQS

Your questions answered

Mounjaro is designed for weight loss and should only ever be used by an individual who’s overweight or obese. A clinician will carry out an assessment and determine whether it’s a safe and effective treatment for you. They’ll ask you about your lifestyle, any medications you’re taking, and treatment preferences. You can do a consultation online.

Successful weight loss with Mounjaro involves more than just medication. Adopting healthy lifestyle habits is a key component to improving overall health and losing weight. This includes a balanced diet, regular physical activity, adequate sleep, and stress management. Combining Mounjaro with these lifestyle changes can significantly enhance weight loss and your overall health.

Clinical trials have demonstrated that Mounjaro leads to significant weight loss by reducing appetite and increasing feelings of fullness. Participants in these studies experienced notable weight reduction, making it an effective tool for weight management when used alongside diet and exercise.

The effects of Mounjaro on appetite reduction and weight loss tend to happen within the first few weeks of treatment. However, the timeline can vary from person to person. For many, a noticeable difference in weight and appetite control is evident within the first three months.

The price of Mounjaro depends on the strength of the dose. The market price of the higher strength pens is more than the lower strength pens, and this is dependent on the manufacturer.

The following prices are per month, and exclude potential discounts:

2.5mg: £219

5mg: £249

7.5mg: £299

10mg: £319

12.5mg: £339

15mg: £359

Learn more

Each Mounjaro KwikPen contains 3 ml of liquid. It's designed to deliver 0.6 ml per dose, providing a total of 4 doses per pen. The pen holds more than 2.4 ml of usable liquid to ensure there is enough for priming before each dose.

After you’ve used all 4 doses, it’s normal to see some liquid left in the pen. This leftover medicine means the pen worked correctly. You won’t be able to dial another full dose, so it’s time to throw the pen away, even if there’s some liquid still inside.

Read this blog for more information.

To get all four doses from your Mounjaro KwikPen, follow the priming and dosing instructions in the leaflet inside your medication box or the Patient Information Leaflet. Priming helps get rid of any air in the pen and makes sure it's working correctly. After each dose, you can check the plunger position to confirm the dose was delivered properly.

Read this blog for more information.

If the dose knob on your KwikPen is hard to push, try these steps:

  • Prime the pen before each injection to remove any air. Never apply pressure to the dose knob without a pen needle attached as there’s no path for the medication to go. 

  • Push the dose knob down more slowly; this can make it easier to inject.

  • Make sure you’re using a new, properly attached pen needle each time. If the new needle is faulty or blocked, put on another new needle and prime the pen.

  • Store the pen in a clean, dry place to prevent any dirt or damage.

If these steps don't solve the problem, contact one of our clinicians in the app for assistance.

Health coaches are there to amplify the benefits of your weight loss journey with Mounjaro by helping you integrate sustainable habits in nutrition, exercise, sleep, and mindset.

While Mounjaro suppresses appetite and manages blood sugar, your coach provides tailored strategies to help you sustain this progress, such as setting achievable goals, keeping you motivated, and offering a balanced approach to nutrition and fitness.

Our nutrition philosophy complements Mounjaro’s effects by focusing on balanced, sustainable changes that fit your lifestyle. Mounjaro helps keep you feeling full, reducing cravings for high-calorie foods, while our health coaches provide practical guidance on nutrient-rich foods that fuel your body. Together, these approaches aim to create a dietary shift that promotes long-term success and reduces dependence on fad diets.

Learn more about our approach to nutrition and how it pairs with Mounjaro to support effective, lasting weight loss.

References

*Based on a retrospective study in 2,366 patients treated with a weightloss programme including a dual GLP-1 and GIP receptor agonist and a digital behavioural programme. Results seen after 3 months of treatment. Uplift attributed to the digital behavioural programme in patients with no prior use of weight loss medication. Individual results may vary based on lifestyle, usage of the app, and interactions with behavioural coaching.

1 Based on the SURMOUNT-1 phase 3 RCT (Jastreboff et al., 2022 - DOI: 10.1056/NEJMoa2206038), conducted alongside a lifestyle intervention. Results represent estimated outcomes at the 15mg dose based on full adherence, in a clinical trial population; individual results will vary.

2 Lin F, Yu B, Ling B, Lv G, Shang H, Zhao X, et al. Weight loss efficiency and safety of tirzepatide: A Systematic review. PloS one. 2023;18(5): e0285197.

3 Tirzepatide for managing overweight and obesity. Nice.org.uk. https://www.nice.org.uk/guidance/ta1026/documents/draft-guidance-2 [Accessed 15th May 2025].

4 Based on the STEP UP phase 3b RCT (Wharton et al., 2025 - DOI: 10.1016/S2213-8587(25)00226-8), conducted alongside a lifestyle intervention. Results represent estimated outcomes based on full adherence, in a clinical trial population; individual results will vary

5 Lee A, Cardel M, Donahoo WT. Social and Environmental Factors Influencing Obesity. [Updated 2019 Oct 12]. In: Feingold KR, Anawalt B, Blackman MR, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK278977/

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