All content on this page has been medically reviewed by: Hassan Thwaini, Clinical Pharmacist and Copywriter, Master of Pharmacy (MPharm) on 30 March, 2026. GPhC Registration: 2221320View profile
Your body's been making creatine since before you could walk.2 It lives in your muscles, quietly topping up the energy you burn through short, intense effort: sprinting for the bus, the last few reps, anything that asks a lot of you in a short window. We just give it a hand with a single dose of creatine monohydrate, the most researched form there is.2,3
At least 3g of daily creatine increases physical performance in successive bursts of short-term, high-intensity exercise.1
Getting older doesn't have to mean getting weaker. Daily creatine consumption can enhance the effect of resistance training on muscle strength in adults over the age of 55.4
Losing weight and losing muscle aren't supposed to be a package deal. Resistance training can help you hold onto muscle while losing weight quickly.5
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When you lose weight quickly on a GLP-1 medication, you're not just losing fat. Clinical data suggests 25 to 39% of that weight can be lean mass, made up largely of muscle, which affects strength, metabolism, and how well you keep weight off long term.6
A 2024 review of supplement use during GLP-1 therapy landed on a straightforward conclusion. Daily creatine, paired with resistance training, belongs in the plan itself, not as an optional add-on.5
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Creatine intake from food alone is much lower than the amounts studied in supplementation, which means most people have room to benefit. Baseline creatine stores tend to be lowest in older adults and in vegans and vegetarians, who get little to no creatine from their diet.5
Adults over 55 who want to help maintain strength and muscle as they age, alongside regular resistance training.
Anyone who trains regularly and wants to support exercise performance.
Creatine monohydrate is the most researched and bioavailable source of creatine. Each serving (3.45g) contains 3g of creatine from creatine monohydrate, which is the dose required to achieve the physical performance and muscle strength benefits above.*
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Dr James King
Chief Medical Strategy Officer
MBBS MPhil PhD
Danielle Brightman
Clinical Director
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Dr Tsolmon Tsogbayar
Senior Clinical Product Lead
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Dr Michael Lacey
Numan Doctor
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Dr Dimitris Schizas
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VP of Behavioural Medicine
BSc (Hons) RD SCOPE
Victoria Rogers
Head of AI Coaching and Behavioural Science
MSc BSc
1. Food and feed information portal database. Europa.eu. [accessed 15 July 2026] Available from: https://ec.europa.eu/food/food-feed-portal/screen/health-claims/eu-register/details/POL-HC-6365
2. Persky AM, Brazeau GA. Clinical pharmacology of the dietary supplement creatine monohydrate. Pharmacol Rev. 2001;53(2):161–76
3. Antonio J, Candow DG, Forbes SC, Gualano B, Jagim AR, Kreider RB, et al. Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show? J Int Soc Sports Nutr. 2021;18(1):13.
4. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). Creatine in combination with resistance training and improvement in muscle strength: evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006. EFSA J. 2016;14(2):4400.
5. Ribeiro F, Forbes SC, Candow DG, Perim P, Kerksick C, Johnson K, et al. Creatine supplementation for preventing muscle atrophy in patients taking incretin-based pharmacotherapies: a perspective. The Journal of Nutritional Physiology. 2026;(100028):100028.
6. Eisa N, Barood O. Lean mass changes with incretin therapy versus lifestyle intervention: A systematic review and meta-analysis of randomised controlled trials. Diabetes Obes Metab. 2026;28(6):4818–27.
7. Buford TW, Kreider RB, Stout JR, Greenwood M, Campbell B, Spano M, et al. International Society of Sports Nutrition position stand: creatine supplementation and exercise. J Int Soc Sports Nutr. 2007;4(1):6
Medically reviewed:
Dr James King
Chief Medical Strategy Officer
MBBS MPhil PhD
Danielle Brightman
Clinical Director
MPharm PgDip PCert
Dr Tsolmon Tsogbayar
Senior Clinical Product Lead
MBBS MSc
Dr Michael Lacey
Numan Doctor
MBChB BSc (Hons) MRCGP
Dr Dimitris Schizas
Numan Doctor
MBBS MRCGP MSC BSSM
Zoe Griffiths
VP of Behavioural Medicine
BSc (Hons) RD SCOPE
Victoria Rogers
Head of AI Coaching and Behavioural Science
MSc BSc
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